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Sequential fluid Injection pack

Multiple fluid switching pack

Quickly swap between 12 or more fluids (gas or liquids) at a controlled flow rate
Multiple fluid injection

Quickly swap between up to 12 (or more) fluids (gas or liquids)

High Stability and precision

Switch fluids while maintaining highly stable and accurate flow rate

Microfluidic Workflow Automation

No more time consuming experiment

High versatility

Use it with any fluidic system

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This pack includes all the necessary elements to sequentially inject up to 12 (or more on request) solutions in a fully automated fashion using our computer-controlled 12 to 1 MUX Distribution bidirectional valve, high accuracy OB1 flow controller, and intuitive ESI control software.

A large flow rate range (from 7 nL/min to 30+ mL/min) and volumes (100 µL to up to several Liters) are accessible with this system.

The typical Sequential fluid injection pack setup uses only one single pressure channel to sequentially flow multiple solutions into your microfluidic system. Medium change can then easily be carried out using the MUX Distribution‘s rotary valve that acts as a liquid selector and allows fast switching and selection between your solutions.

In combination with an MFS or BFS flow sensors, the OB1 flow controller allows an extremely stable liquid perfusion (down to 0.006% of the flow rate).

All these operations can be performed using the ESI software interface. The software allows you to fine-tune the flow parameters as well as to automate your experiment using our intuitive scheduler.

Advantages

  • A large number of samples: Possibility to sequentially inject up to 12 (or more) solutions in your system
  • Stable & pulseless flow rate: Very stable fluid delivery for most accurate results thanks to our pressure-driven flow controller
  • High versatility: Use it with any fluidic system such as microfluidic chip, sensor test rigs, flow chemistry setup
  • Perform fast switches between media: Switching time below 150 ms
  • For small and large volume for long term experiments: Work with volumes from few µL to several liters
  • Control both pressure & flow rate: For maximum versatility on your fluid injection
  • A broad range of flow rates accessible: From 7nL/min to 30+ mL/min with an accuracy down to 0,2%
  • Design flow injection sequences: Create complex patterns and fully automatize your system to test any working conditions over hours or days
  • High parallelization possibilities: Test multiple devices with one setup
  • Software development kits: in C, LabView, Matlab, and Python for integration into your platform.

How to perform microfluidic multiple liquid switching?

Mux Distribution Valve, fluid switching in a microfluidic chipMore information on how to perform a stable and precise flow switch in our example application note.

Our sequential fluid injection pack can be adapted for more complex and advanced experiments such as using 20 or more solutions, removing bubbles, integration into larger systems or testing multiple chip/devices simultaneously…

Contact us to know more!

Microfluidic multiple liquid switching system

  • Computer: Control all the parameters with our software, & automate your experiment by creating injection sequences
  • Pressure & flow controller: Impose a given pressure in order to create a stable and pulseless flow rate
  • Manifold: Split the pressure path to pressurize multiple reservoirs with a single pressure controller
  • Reservoirs: Contain your medium or samples. Various sizes are available, from Eppendorf to bottles
  • Rotary valve: Select the injected liquid
  • Flow Sensor: Monitor & control the flow rate in real-time
  • Microfluidic chip: any fluidic system can be hooked up to our fast fluid switching pack

Complete Userguide | Automated Fluid Sequential Injection

To discover more tips and tricks…

Get in touch to claim our complete Userguide about Automated Fluid Sequential Injection!

Userguide Fluid Sequential Injection

The sequential fluid injection pack can be used in various fields of application and for any experiment that require successive injection of fluids: from organic synthesis, flow chemistry, drug screening, biochemical and electrochemical sensor calibration, calibration (bench testing), sensors test rig, toxicity test, Seq-Fish experiment…

Publications

Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction

T. Qian et al., Lab on a  Chip, 2020, 20, 3744-3756, DOI: 10.1039/D0LC00546K

Microfluidic platform for 3D cell culture with live imaging and clone retrieval

C. Mulas et al., Lab on a chip, 2020, 20, 2580-2591, DOI: 10.1039/D0LC00165A

The amazing benefits of microfluidics can be applied to almost any application and therefore the content of the Sequential fluid injection Pack can be adjusted to suit your specific needs. Contact us for more details.

CONTENT

  1. Pressure & flow controller (OB1)
  2. Rotary valve (MUX Distribution)
  3. Microfluidic flow sensor (MFS) or high accuracy BFS sensors
  4. Reservoirs
  5. Pressure splitter manifold
  6. Tubing and connectors
  7. Software and SDK libraries (C++, Python, MATLAB, LabVIEW)

OPTIONS

  • Additional pumping channels
  • Additional flow rate sensors
  • Microfluidic chip
  • Computer
  • Manifold

Multiple Liquid switch videos

 

 

Related microfluidics webinars

colored bubble

Testimonials

Sequential Fluid Injection Webinar

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Software

A free software for all instruments

Powerful, modular and versatile set-up control solution

The ESI software can control up to 16 Instruments through the same interface. Thanks to TTL triggers you can synchronize your Elveflow system with any other instrument used in your laboratory (microscope or any electrical instrument … ). The Scheduler is a user-friendly tool to automate complex steps of your experiments and protocols.

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Volume
Injection
module

Enter your targeted volume and this module will automatically adjust the flow rate at the right time to inject it.

Fluidic system optimization module

Automatic diagnostic of the fluidic path sizing and recommendations to improve your microfluidic setup.

Bubble
detection
module

Do not suffer anymore because of bubbles!

Sensor calibration module

Don’t lose precious time in calibration protocols.

Need help or advice?

For any help to determine what microfluidic instruments you need, you can contact us!
Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.

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