Organ-on-a-chip pack

Elveflow’s Organ-On-Chip Pack setup uses one flow controller to flow a medium through a chip containing the organ cells. The software allows a very accurate and stable control of the flow rate over defined periods of time.

Fully customizable pack 

Whether you want to add multiple fluidic channels, customize your microfluidic chip or add a vacuum control, our microfluidic specialists can customize the pack so that it can best fit your experimental needs.

Contact us for more information!

Organs-on-chips applications do not only have several advantages such as miniaturization, integration and low consumption, but also they allow researchers to accurately control the multiple parameters of a system such as chemical concentration gradient, fluid shear stress, cell patterning, tissue-tissue interface, organ-organ interaction and so on. They aim at mimicking the complex structure, microenvironment and physiological function of human organs.

These applications hold the promise of having a significant impact on improving the predictability of drug screening models and personalized medicine. Organ-on-a-chip technology supports these research areas by providing an environment that can mimic the human physiology and morphology in vivo better than traditional static cell culturing methods. Scalable organ-on-a-chip production is made possible by combining the technologies originating from both the semiconductor and molecular biology industries.

Organ-on-chip microfluidic devices

The Organ-On-Chip Pack can be used with any commercial chip or self-made chip.

ChipShop is a company offering versatile chips for several applications including 3D cell culture and organ-on-a-chip. Particularly, the cross flow membrane chip (Fluidic 480) enables to create a tissue interface to mimic organs functions (gut-on-chip, brain-on-chip, kidney-on-chip, skin-on-chip, etc.).This chip hosts two different culture chambers separated by a permeable membrane. Different cell types can be seeded on one or both sides of the membrane and exposed to dynamic flow conditions.

Microchip with 2 independant chambers for organ on chip studies

There are several chip designs available for organ-on-chips experiments, depending on the type of organs that scientists would like to mimic and the experimental protocols. Elveflow is working closely with several organ-on-chips providers to supply the most suitable chip for your science.

• ChipShop
• Ibidi
• BeOnChip
• Initio Cell
• Synvivo
• MesoBioTech

To help you determine your flow rate, pressure to apply, the best tubing resistance length for your setup, wall shear stress for biology applications, cell culture, and many more…

Elveflow provides its microfluidic calculator and…to make the most of our microfluidic calculator, find below a set of dedicated application notes:

• What is a microfluidic calculator?
• Viscosity conversion
• Shear stress calculator
• How to calculate the flow rate with microfluidics 
• Microfluidic resistance calculator