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The liquid stream flows continuously in the same direction
Don't be limited by your sample volume: recirculate your medium
Same flow direction ensures no variations in shear stress
Automate your experiments for several days
A standard Recirculation Pack setup uses two pumping channels to alternatively flow medium from one reservoir to another. An injection valve allows to switch between both reservoirs, to ensure that the medium is pumped from the most filled reservoir. The injection loop consists of a network of inputs/outputs that can be connected to each other in two configurations. Its very low internal volume (2.5 μL) makes it the ideal valve to perform the injection of a controlled volume of sample into a chip.
The Elveflow® smart interface (ESI) synchronizes the flow controller together with the injection valve in order to perform recirculation. It performs the switch between reservoirs automatically either after a predetermined period of time or, in combination with a the flow rate sensor (MFS), after a chosen amount of sample has gone through the chip. The software is also able to seamlessly run long term experiments thanks to its powerful scheduler.
Additional features such as medium switch, one-off sample injection, etc… are also possible by adding extra Elveflow’s equipment to your Recirculation Pack.
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To help you determine your flow rate, pressure to apply, the best tubing resistance length for your setup, wall shear stress for biology applications, cell culture, and many more…
Elveflow provides its microfluidic calculator and…to make the most of our microfluidic calculator, find below a set of dedicated application notes:
Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction
T. Qian et. al, Lab on a Chip, 2020, 20, 3744-3756, DOI: 10.1039/D0LC00546K
Investigation of flow dynamics and structure in channels with structured surfaces
P. Vilkinis, 2020, Doctoral Thesis, Kaunas University of Technology, Lituanian Energy Institute
A standard Recirculation Pack contains the following:
“I appreciate rapid setup time and the fact that we can very precisely adjust the flow rates through the user-friendly interface. The dynamic and responsive engineering team was an additional benefit.”Dr. Caglar Elbuken, UNAM - Bilkent University, TurkeyOB1 pressure-driven flow controller user
“We really appreciate the stability and low response time of the flow controller, which is important when various flow conditions must be applied successively. The flow can be precisely and easily controlled thanks to a user-friendly interface. ”Dr. Marie Frénéa-Robin, Laboratoire AMPERE, Université Claude Bernard LYON 1, FranceOB1 pressure-driven flow controller user
“We are very satisfied with the Elveflow instruments, the pressure ranges are very useful for our applications.”Dr. Rémy Fulcrand, Liquid & Interfaces’ Group of PMCN Laboratory – CNRS UMR5586 at Claude Bernard Lyon 1 University, FranceOB1 pressure-driven flow controller user
For any help to determine what microfluidic instruments you need, you can contact us! Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.
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