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Alginate beads generation pack

Alginate beads generation

Alginate beads generation system straight out of the box! All you need to know to perform hydrogel particle production!
Easy micron size beads generation

Unbox, set up and start your experiments using our application note

Reproducible & high monodispersity

Produce monodisperse hydrogel beads (PDI <5%)

Perfect for many applications

Including drug delivery, wound healing, cell & tissue culture

Talk to an expert

A standard alginate beads generation pack contains one pumping channel to flow the aqueous alginate phase and another pumping channel to push the continuous oil phase through our droplet generation chip, enabling the generation of alginate droplets in oil.

The droplet size will be determined by the chip channel size and the flow rate ratio of both phases. Flow rates can be measured thanks to our multiple flow rate sensors (MFS or BFS series).

For the detailed experimental steps, please refer to our application note!

Microfluidic setup to generate alginate droplets with a microfluidic chip

User guide alginate beads production book

User guide alginate beads production

    Add your email adress to receive the user guide

    To help you determine your flow rate, pressure to apply, the best tubing resistance length for your setup, wall shear stress for biology applications, cell culture, and many more…

    Elveflow provides its microfluidic calculator and…to make the most of our microfluidic calculator, find below a set of dedicated application notes:

    Publications

    Droplet microfluidics as a tool for production of bioactive calcium phosphate microparticles with controllable physicochemical properties, P. Habibovic et al., Acta Biomaterialia (2021).

    3D flow-focusing microfluidic biofabrication: One-chip-fits-all hydrogel fiber architectures, Rui L. Reis et al. , Applied Materials Today (2021).

    Additive batch electrospinning patterning of tethered gelatin hydrogel fibres with swelling-induced fibre curling

    Elisabeth L. Gill, Wenyu Wang, Ruishan Liu, Yan Yan Shery Huang, Additive Manufacturing, 2020, Volume 36, 101456, DOI: 10.1016/j.addma.2020.101456

    Highly Ordered Gelatin Methacryloyl Hydrogel Foams with Tunable Pore Size

    Friederike Dehli, Lisa Rebers, Cosima Stubenrauch, and Alexander Southan, Biomacromolecules 2019 20 (7), 2666-2674 DOI: 10.1021/acs.biomac.9b00433

    The amazing benefits of microfluidics can be applied to many droplet applications and therefore the content of the alginate pack can be adjusted to suit your specific needs. Contact us for more details.

    CONTENT

    Options

    • Additional pumping channels
    • Additional flow rate sensors
    • Computer
    • Microscope and camera

    Videos

    colored bubble

    Testimonials

    Why choosing microfluidics for alginate beads generation?

    Microfluidics brings reproducibility and control over particle or droplet size that is not achievable by any other technique. Continuous hydrogel beads generation with constant size and flow rates control, results in highly monodisperse particles (PDI < 5%).

    Moreover, microfluidics is an ideal technique for handling ultra small volumes and control what goes into each droplet or bead. Microfluidics give you flexibility to easily generate identical carrier with the same content. For more detailed protocole about alginate beads generation, please refer to our application note!

    Configure your alginate pack

    1. Select the right parameters to obtain the desired beads size

    Elveflow offers a specific chip that allows you to generate a broad of range of beads size,  shape and materials. For more information, please refer to our application note about alginate beads generation.

    If you’re unsure about the settings that are best suited for your application, get in touch with one of our experts!

    2. Choose your reservoir size

    Are you working with small samples or are you looking into manufacturing 100x mLs of hydrogel beads solution? Elveflow offers a comprehensive range of  reservoirs compatible with our OB1 flow controller, from 1.5 mL Eppendorf tubes to 100mL bottles.

    Microfluidic adapter for Eppendorf © , Falcon © tubes or GL45 glassware rack

    3. Oil & surfactants

    To make monodisperse and stable alginate beads, Elveflow offers a range of oils and surfactants. For more detailed information, please refer to this application note!

    Interested in highly monodisperse hydrogel beads production?

    Hydrogel-based delivery systems are finding more and more applications, from encapsulation, protection, to the release of bioactive agents in many fields such as pharmaceuticalsupplementsfood industries, for cell/bacteria/microbes culture & implantation, and cell-based genes in biological research.

    Are you interested in implementing hydrogel beads production in your lab?

    Contact us to have your dedicated your dedicated hydrogel beads generation pack that suits your application needs!

    Alginate beads generation 2

    Highly monodispersed alginate droplets, size in the 50µm range. Experiment results by  the Elveflow team.

    Need help or technical information?
    Talk to an expert

    Need help or advice?

    For any help to determine what microfluidic instruments you need, you can contact us!
    Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.

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