MAGNETICS AND MICROHYDRODYNAMICS: THE MAMI PROJECT
The MaMi project combines expertise in the field of magnetism with knowledge of bioinspired local flow control, in order to create novel concepts and technological solutions that could revolutionize the field of microfluidics. The MaMi network consists of research teams from France, Germany, Ireland, Latvia, Slovenia, and Spain and engages world-recognized leaders in the fields of magnetism and fluidics.
The MaMi project bridges the research fields of microfluidics and magnetism, by taking advantage of magnetic forces to control local flows and cargo transport inspired by biomimetic systems. The key research question guiding the project is “How can magnetism and biomimetic locally-driven flows overcome the current limitations of microfluidics?”. The 9 MaMi partners will take different approaches to address this question.
In this consortium, Elvesys is going to develop microfluidic devices for organ-on-chip applications with industry potential. The ultimate goal will be to address the hurdles that need to be overcome for transition of microfluidic techniques from prototype-state organ-on-chip into marketable devices.
Currently, PDMS is the gold standard fabrication material within the engineering research community. To design this new generation of organs-on-chips, we will explore fast-fabrication thermopolymer materials (PMMA, PC, PS, COC) that are better suited for biological applications and commercially relevant with scale-up potential. However, as thermopolymers are non-stretchable, the current methods of recreating desirable mechanical stimulation to produce more bio-relevant cellular phenotypes will not be possible. We will therefore exploit magnetic forces to achieve remote mechanical stimulation within the thermopolymer organ-on-chip.
- PhD candidate at Elvesys in the frame of MSCA-ITN
- Analytical chemist (QPharma AB, Sweden)
- Master of Science in Biomedical engineering (Lund University, Sweden)
AREAS OF EXPERTISE: Biomedical engineering, Microfluidics, Organ-on-chip, Magnetism
Have a look at two reviews written by our PhD candidate Emma Thomée, who is currently working on the MaMi project at Elvesys:
Microfluidic Nanoparticle Synthesis: A short review
Magnetic fluids and microfluidics: A short review