FIT-UTI: Fully Integrated Technology for the diagnosis of Urinal Tract Infection

The project aims at developing a low-cost and reliable microfluidic disposable cartridge and the corresponding plug-and-play operating system for ultra-fast point-of-care diagnosis of UTI (Urinary Tract Infection) disease. It is an ongoing project funded by European Commission H2020 Individual Fellowships, Society and Enterprise panel (Project ID: 750999).

FIT-UTI--Fully-Integrated-Technology-for-the-diagnosis-of-Urinal-Tract-Infection-Elveflow

Urinary tract infection (UTI) is a symptomatic bacterial infection that occurs within the urinary tract. It is estimated that 15% of all community-prescribed antibiotics in some EU countries are dispensed for UTI2. Within this FIT-UTI project, a novel and proprietary lab-on-a-chip system integrating urine sample pretreatment and quantitative polymerase chain reaction (qPCR) for bacteria gene recognization in point-of-care UTI diagnostics will be developed.

This project will be based on the Elvesys proprietary FASTGENE technology. The prototype will be expected to perform bacteria filtration, lysis, DNA extraction and PCR full-automatically. It will provide a reliable diagnosis from the urine sample input to fluorescence readout in less than 15 minutes. This technology can be extended to other disease diagnostics as well thus contributing to solving the current EU needs for fast point-of-care diagnostic technologies.

1. The  picture comes from website of Centers for Disease Control and Prevention, USA
2. Guidelines on urological infections, European Association of Urology, 2015

SISI-LI-elveflow-microfluidics

Researcher

Dr. Sisi LI

PI of Marie Curie Individual Fellowship

  • Research fellow of NTU & SIMTech, A*STAR, Singapore
  •  PhD & Postdoc of CNRS-ENS-UMPC, France
  • 14 publications- 2 patents- H index 7

Area of expertise: Microfluidics, Micro & Nanoengineering of cell microenvironment, Cell biology, MEMS, Biomaterials

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