AutoDropProd: Automated high-throughput production of monodisperse emulsions with microfluidics

Monodisperse emulsions are of great interest for food industry, pharmaceutical industry and cosmetics industry as they have an increased stability and better controlled properties compared to the polydisperse ones.

AutoDropProd_microfluidic_monodisperse_emulsion-Elvesys-principle

Thanks to the success of AutoMonoDroplet project, we are now able to automatize the production of specific size droplets at rates higher than 5 kHz in microfluidics chips and to precisely control their size, making monodisperse emulsions with a coefficient of variation  below 0.2%. This is achieved by measuring the droplet size using optical methods based on our Optoreader and constantly adjusting the droplet diameter by changing flow rates and pressures. To achieve the best results we are using the fast response Elveflow flow control system, thus improving the performance of the system.

The production of monodisperse emulsions in a single channel is already well controlled, thus we will concentrate in this new project on the high-volume droplet production to meet industrial needs.  We aim to apply parallelized droplet generators in combination with controlled automated droplet production to provide monodisperse emulsions despite any fluctuations in the system (for example the clogging of a microfluidic channel or other instabilities).

Additionally, when using the combination of our developed system with an adjustable chip geometry, one can produce droplets of almost any desirable size using single chip, thus avoiding droplet size limitation imposed by the channel dimensions.

As a result, we will be able to offer a very versatile, stable and simple to use microfluidic system to perform the generation of specific size monodisperse emulsions at an industrial scale.

AutoDropProd_microfluidic_monodisperse_emulsion-Elvesys-parallelization

This project has received funding from the European Union’s Horizon 2020 MSCA-IF under grant agreement No 796514 (AutoDropProd).

02_Droplet_detection_tool_ELVEFLOW_MICROFLUIDICS (2)

AutoDropProd: Simulatious droplet detection and size regulation.

Droplet Detector

AutoDropProd_microfluidic_monodisperse_emulsion-Elvesys-REMIGIJUS_VASILIAUSKAS

RESEARCHER

Dr. Remigijus Vasiliauskas

Research Associate

  • R&D Engineer in Digital Microfluidics
  • Post-Doc in Digital Microfluidics and Drug Delivery (Vilnius University, Lithuania)
  • PhD in Physics (Linkoping University, Sweden)
  • Master of Science in Material Sciences (Vilnius University, Lithuania)
  • 27 publications, 320 citations, h-index 12

AREAS OF EXPERTISE: Digital Microfluidics, Microtechnology, Soft Lithography, Semiconductor Technology and Sensors

NEED TO GENERATE MONODISPERSE DROPLETS FOR YOUR RESEARCH CONSORTIUM ?

Guilhem Velvé Casquillas

Drop me a line

You have a research project in mind and you are looking for an industrial partner in microfluidics ?

I will study your proposition and come back to you quickly to find together the best way to collaborate on your project. If the submission deadline is coming soon,  I will try to come back to you on the same day.

Since all of us initially came from public research lab, we are used to collaborate with research laboratories inside scientific consortium and new scientific projects are always welcomed.

Feel free to write me and ask for Guilhem at: contact@elveflow.com

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