3D-printing of microfluidic MEMS for Lab-on-a-chip applications: the M3D-Loc project
The detection of a disease at an early stage increases the chance of recovery.
Microfluidic lab-on-a-chip, allowing the reduction of volume samples and analysis time as well as improving the sensitivity, is a promising technology for the development of efficient and portable diagnostic devices. However, the upscaling of lab-on-a-chip technology remains challenging.
3D-printing facilitates the production of microfluidics devices, offering an affordable and easy alternative to produce labs-on-chip in a reproducible way.
M3D-LoC consortium is gathering 18 industrial and academic partners from 9 countries to develop the next generation of 3D-printed microfluidic devices for diagnosis. A pilot line combining different manufacturing techniques to produce microfluidic chips with a good resolution and a low rugosity will be built, and the performance of this new manufacturing platform will be evaluated by designing novel lab-on-chip devices for the detection of three diseases: tuberculosis, HIV and lung cancer.
In this consortium, Elvesys will use its expertise in microfluidics and microfabrication to design the 3D-printed microfluidic chips, allowing the extraction, purification and detection of DNA from human plasma. The flow control systems (valve and pressure controllers, pumps…) already commercialized by our company should help to perform all the steps involved in diagnosis.
This project has received funding from the European Union’s Horizon 2020 IND-CE under grant agreement No 760662 (M3D-Loc project).