microfluidic-droplet-pack

Feature & Benefits
Up to 10 000 droplets/sec
Flow rate: from 0.1 µL/min to 5 mL/min
Droplet size dispersion: 0.4%
Change of droplets content : 100 ms

Droplet generation Pack

This pack had been designed to fit most common droplet generation needs of researchers. Many options are available and the pack is fully customizable & upgradeable , feel free to contact us.

Easily generate microfluidic droplets

Elveflow® provides a microfluidic droplet generation pack to help any research lab to easily generate droplets into a microfluidic chip. This fully integrated solution includes all the necessary elements to easily create droplets.

Fast & Reproducible droplet generation

Change in one click droplet size, production rate and content. Using the world highest performance microfluidic flow control system, this pack provide you a droplet generator at the state of the art.

An open setup with access to all parameters

While giving you the opportunity to easily generate droplet,  Elveflow gives you access to all parameters and options to enable you to do the exact experiment you need.

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Your needs

HIGH DROPLET FREQUENCY

Up to 10 thousands droplet per second

Slow motion of fast droplet generator using Flow Focusing chip.

FAST CONTENT SWITCH

Change content in 100 ms

Slow motion of medium switch through sinus function.

REPRODUCIBLE

A size dispersion down to 0.4%

 Uniform drop generation using T-junction chip.

Piezo Technology for droplet generation

This droplet pack is based on our unique piezoelectric flow control technologies which enable user to perform world fastest flow switch while keeping the smallest flow stability reachable in microfluidics. Equipments used in this pack had been chosen by main innovating actors in the field of droplet such as Sphere Fluidics, deMello group and Bibette’s lab.

Piezo electric microfluidics flow control

Step by Step

Install a droplets setup in 4 steps

Microfluidic droplet generation Pack tankSTEP 1 

Microfluidic tanks

Fill your tanks with dispersed and continuous phase.

OB1-MK3-microfludic-flow-control-system- microfluidic droplet generation setupSTEP2

Flow controller 

Plug tanks, chip and flow controller together.

STEP 3

Software

Launch Elveflow software and set your parameters.

Microfluidics droplet flow focusing emulsion science on chipSTEP 4

Microchip

Click and tubing will be automatically filled and droplet generation will start in your chip.

How it work ?

microfluidic droplet emulsion T-junction pressure control

  1. Continuous and dispersed phases are contained into microfluidic tanks.
  2. The pressure controller pressurize microfluidic tanks and generate a pulseless flow of continuous and dispersed phases from tanks to microchip.
  3. Droplets are generated in the microchip. Their size, speed and composition will depend of flow rate of liquid coming from microfluidic tank.
  4. Changing parameter into the software will almost instantaneously change pressure of tank and then  flow rate of liquid entering into the chip.

Need advice to do microfluidic droplets ?

Guilhem Velvé CasquillasOur microfluidic R&D team will be glad to answer you

Feel free to write us at: contact@elveflow.com

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Features & benefits

> Smallest droplet size dispersion  : 0.4%

Reach the smallest droplet size dispersion of the litterature thanks to our pulseless pressure controller (0.005% stability)

> Fast change of droplets content : 100 ms

Thanks to our piezoelectric pressure regulators change the content of your droplet in 100ms. Test hundreth of experimental conditions in minutes.

> Wide range of droplet frequency up to 10 000 droplets/sec

Modularity of this pack and ability to generate flow rate from 0.1 µL/min to 5 mL/min enabling droplet frequency up to 10 kHz.

> Long term experiment : up to month …

Our microfluidic pressure regulators is the only one on the market which is able to work with large tank volume up to several liters while keeping responsiveness. Using our bottle tank perform long term experiment even at high flow rate.

> Programmable droplet sequences

Using our smart software interface control your droplet generation in real time our using programmable sequencer.

> Flexible pack

You have access to all parameter to customize your experiment and for your best convenience, you can use your own chip or use droplets chips provided by Elveflow. You can also choose between four size of tank, 1,5 mL eppendorf, 15 & 50 mL falcon or bottles.

DROPLET Pack Content

Enable to accurately create and manage pulseless flow.

Enable to manage flow rate while using pulseless flow.

Load your different phases producing droplets.

Needed accessories to connect all items together.

Silicon, mineral or fluorinated? Main oils for droplets.

Manage size, frequency and speed of droplets.

Several Version of Microfluidic Droplet Pack

Millifluidic Droplet Pack
free copyright milli fluidic dropplet device on microscope

  • Up to 1 000 drops per second
  • Drops’ sizes polydispersity down to 1%
  • Drops’ volume down to few µL

pack’s additional contents

  • 2x ETFE  T-junction – ø 500 µm
  • 1x ETFE Cross jonction – ø 500 µm

“Ideal for fast proofs of concepts experiments.”

PDMS Droplet Pack
Microfluidics droplet Co-flowing emulsion science on chip

  • Up to 10 000 drops per second
  • Drops’ polydispersity down to 0.6%
  • Drops’ volume down to few nL

pack’s additional contents

  • Glass/PDMS/PDMS chip
  • and/or SU-8 Mold for chips production
  • and/or Mold and Chip production Pack

“Best price / performance ratio.”

Glass Droplet Pack
DROPLET glass Introduction to lab-on-a-chip 2015 review history and future chip

  • Up to 4 000 drops per second
  • Drops’ polydispersity down to 0.4%
  • Drops’ volume down to several pL

additional pack’s contents

  • Glass droplet microfluidic chip
  • Tubing to chip connectors

“Premium conditions for digital microfluidics experiments.”

The size, monodispersity, and production rate of droplet is function of several parameters, including: Flow stability, Viscosity of fluids, Presence of surfactants, Use of coatings on channel walls, Surface tension between fluids, Surface tension between fluids and wetted materials

Glass Microfluidic Droplet Pack - Available options

Microfluidic Chip Droplet F 20 micron
Glass microfluidic droplet chip t junction

Flow focusing droplet generator

The Microfluidic Chip Droplet F 20 micron is a complete glass microfluidic device & chip interface designed for droplets generation. The Microfluidic Chip Droplet F 20 micron is composed of :

  • Flow focusing droplets generation geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  20 µm / width = 100 µm
Microfluidic Chip Droplet F 100 micron
Glass microfluidic droplet chip t junction

Flow focusing droplet generator

The Microfluidic Chip Droplet F 100 micron is a complete glass microfluidic device & chip interface designed for droplets generation. The Microfluidic Chip Droplet F 100 micron is composed of :

  • Flow focusing droplets generation geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  100 µm / width = 500 µm
Microfluidic Chip Droplet T 20 micron
Glass microfluidic droplet chip t junction

T junction droplet generator

The Microfluidic Chip Droplet F 20 micron is a complete glass microfluidic device & chip interface designed for droplets generation. The Microfluidic Chip Droplet F 20 micron is composed of :

  • T-junction droplets generation geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  20 µm / width = 100 µm
Custom Made Droplet Chip
DROPLET glass Introduction to lab-on-a-chip 2015 review history and future chip

Droplets at your conditions

We can provide a complete glass microfluidic device & chip interface designed for droplets generation. We will study your request and provide you further information and quotation. Please provide us:

  • Your mask design
  • Specific requirements

Features and benefits

  • Hydrophobic or hydrophylic coatings
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Operating pressure up to several decades of bar
  • Several chip layers thicknesses

More options available below

Applications of droplet generator

Single Cell manipulation

single cell plug and play microfluidic setup

Objects encapsulation

MICROFLUIDICS-DROPLET-DRIPPING-REGIME-T-JUNCTION-

Chemical microreactor

Introduction to lab-on-a-chip 2015  review history and future biomems

Chemotaxis

microfluidic-device-stamping-gradient-flow-control

Specific needs? Several options available to upgrade your pack

This pack had been designed to fit most common droplet generation needs of researchers. Whatever feel free to contact us to discuss with us about your exact need and if necessary we will adapt the pack and chips to your particular research application. Moreover for most common additional needs we already propose on the shelf option.

OPTION

microfluidic-sample-perfusion-injection-switch-valve for microfluidic droplet generation

OPTION

Microfluidic multiplexer MUX Flow switch

OPTION

OPTION

 Optical detection

10 samples switch

Adding Elveflow MUX distributors to this pack enable you to change composition of your droplets between ten different samples during the same experiment.

Stop your droplets in 100 ms

Adding Elveflow valve matrix enable you to start and stop your droplets in 100 ms. The use of valve remove backflow and residual flow and then enable fast flow stop.

Full custom OEM

Need full custom OEM droplet generator for your commercial system ? We have a team with strong knowledge in droplet generation and industrialization. Feel free to contact us to exchange about your specific need.

Fluo droplet tracking

When adding our fluorescence optoreader to our pack you can follow in real time the fluorescence signal of your droplet on your software. This system enable to both excite and collect fluorescence signal  of your droplet and then to detect and quantify any event of interest during your experiment.

WORLD LEADER IN HIGH PERFORMANCE MICROFLUIDIC FLOW CONTROL

We  provide the only microfluidic flow control system using Piezo technology that enables a blazing fast flow change in your microdevice.

Piezo electric microfluidics flow control

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