microfluidic-droplet-pack

Feature & Benefits
Up to 10.000 droplets/sec
Flow rate: from 0.1 µL/min to 5 mL/min
Droplet size dispersion: 0.4%
Change of droplets content : 100 ms

Droplet generation Pack

This pack had been designed to fit most common droplet generation needs of researchers. Many options are available and you can fully customize and upgrade the pack. Feel free to contact us.

Easily generate microfluidic droplets

Elveflow® provides a microfluidic droplet generation pack to help any research lab to easily generate droplets into a microfluidic chip. This fully integrated solution includes all the elements necessary to easily create droplets.

Fast & Reproducible droplet generation

Change in one click droplet size, production rate and content. Using the world’s highest performance microfluidic flow control system, this pack provides you with a state of the art droplet generator.

An open setup with access to all parameters

While giving you the opportunity to easily generate droplets,  Elveflow gives you access to all the parameters and options to allow you to do the exact experiment you need.

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Your needs

HIGH DROPLET FREQUENCY

Up to 10 thousands droplets per second

Slow motion of fast droplet generator using Flow Focusing chip.

FAST CONTENT SWITCH

Change content in 100 ms

Slow motion of medium switch through sinus function.

REPRODUCIBLE

A size dispersion down to 0.4%

 Uniform drop generation using T-junction chip.

Piezo Technology for droplet generation

This droplet pack is based on our unique piezoelectric flow control technology which allows the user to operate the world’s fastest flow switch, with the smallest variation in flow stability that you can reach in microfluidics. The equipment used in this pack was chosen by main innovating actors in the field of droplets, such as Sphere Fluidics, deMello group and Bibette’s lab.

Piezo electric microfluidics flow control

Step by Step

Install a droplets setup in 4 steps

Microfluidic droplet generation Pack tankSTEP 1 

Microfluidic tanks

Fill your tanks with the dispersed and continuous phase.

OB1-MK3-microfludic-flow-control-system- microfluidic droplet generation setupSTEP2

Flow controller 

Plug tanks, chip and flow controller together.

STEP 3

Software

Launch Elveflow software and set your parameters.

Microfluidics droplet flow focusing emulsion science on chipSTEP 4

Microchip

With just one click, tubing will be automatically filled and your chip will start generating droplets.

How does it work ?

microfluidic droplet emulsion T-junction pressure control

  1. Continuous and dispersed phases are contained in the microfluidic tanks.
  2. The pressure controller pressurize microfluidic tanks and generate a pulseless flow of continuous and dispersed phases from tanks to microchip.
  3. Droplets are generated in the microchip. Their size, speed and composition will depend on the flow rate of the liquid coming from the microfluidic tank.
  4. Changing parameters in the software will almost instantaneously change the pressure of the tank, and then the flow rate of the liquid entering the chip.

Need advice for your microfluidic droplets ?

Guilhem Velvé CasquillasOur microfluidic R&D team will be glad to answer you

Feel free to write us at: contact@elveflow.com

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Features & benefits

> Smallest droplet size dispersion  : 0.4%

Reach the smallest droplet size dispersion in the literature, thanks to our pulseless pressure controller (0.005% stability rate)

> Fast change of droplets content : 100 ms

Thanks to our piezoelectric pressure regulators, change the content of your droplets in 100ms. Test hundreds of experimental conditions in minutes.

> Wide range of droplet frequency, up to 10 000 droplets/sec

Modular pack, able to generate a flow rate from 0.1 µL/min to 5 mL/min, enabling droplet frequency up to 10 kHz.

> Long term experiment : up to months…

Our microfluidic pressure regulator is the only one on the market compatible with a large tank volume up to several liters, while staying responsive. Use our bottle tank to perform long term experiments, even at a high flow rate.

> Programmable droplet sequences

Using our smart software interface, control your droplet generation in real time with our programmable sequencer.

> Flexible pack

You have access to all the parameters to customize your experiment. For your best convenience, you can even use your own chips, or droplets chips provided by Elveflow. You can also choose between four sizes of tanks: 1,5 mL Eppendorf, 15 & 50 mL Falcon, or bottles.

DROPLET Pack Content

Accurately create and manage pulseless flows.

Manage the flow rate while using pulseless flow.

Load your different phases to produce droplets.

All the accessories you need to connect the items.

Silicon, mineral, fluorinated? Main oils for droplets.

Manage the size, frequency and speed of your droplets.

Several Version of Microfluidic Droplet Pack

Millifluidic Droplet Pack
free copyright milli fluidic dropplet device on microscope

  • Up to 1.000 drops per second
  • Drop size polydispersity down to 1%
  • Drop volume down to a few µL

additional pack contents

  • 2x ETFE  T-junction – ø 500 µm
  • 1x ETFE Cross jonction – ø 500 µm

“Ideal to quickly prove your experiment’s concepts.”

PDMS Droplet Pack
Microfluidics droplet Co-flowing emulsion science on chip

  • Up to 10.000 drops per second
  • Drop polydispersity down to 0.6%
  • Drop volume down to few nL

additional pack contents

  • Glass/PDMS/PDMS chip
  • and/or SU-8 Mold for chips production
  • and/or Mold and Chip production Pack

“Best price/performance ratio.”

Glass Droplet Pack
DROPLET glass Introduction to lab-on-a-chip 2015 review history and future chip

  • Up to 4 000 drops per second
  • Drops’ polydispersity down to 0.4%
  • Drops’ volume down to several pL

additional pack contents

  • Glass droplet microfluidic chip
  • Tubing to chip connectors

“Premium conditions for digital microfluidics experiments.”

The size, monodispersity, and production rate of droplets depends on several parameters, including: Flow stability, Viscosity of fluids, Presence of surfactants, Use of coatings on channel walls, Surface tension between fluids, Surface tension between fluids and wetted materials

Glass Microfluidic Droplet Pack - Available options

Microfluidic Chip Droplet F 20 micron
Glass microfluidic droplet chip t junction

Flow focusing droplet generator

The Microfluidic Chip Droplet F 20 micron is a complete glass microfluidic device & chip interface designed to generate droplets. The Microfluidic Chip Droplet F 20 micron is composed of :

  • Flow-focusing, droplets-generating geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  20 µm / width = 100 µm
Microfluidic Chip Droplet F 100 micron
Glass microfluidic droplet chip t junction

Flow focusing droplet generator

The Microfluidic Chip Droplet F 100 micron is a complete glass microfluidic device & chip interface designed to generate droplets. The Microfluidic Chip Droplet F 100 micron is composed of :

  • Flow-focusing, droplets-generating geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  100 µm / width = 500 µm
Microfluidic Chip Droplet T 20 micron
Glass microfluidic droplet chip t junction

T junction droplet generator

The Microfluidic Chip Droplet F 20 micron is a complete glass microfluidic device & chip interface designed to generate droplets. The Microfluidic Chip Droplet F 20 micron is composed of :

  • T-junction droplets-generating geometry
  • Fluidic interface and connectors

Features and benefits

  • Hydrophobic and hydrophilic coating
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Chip layers thicknesses: 1.8 mm
  • Other channels sections: depth =  20 µm / width = 100 µm
Custom Made Droplet Chip
DROPLET glass Introduction to lab-on-a-chip 2015 review history and future chip

Droplets at your conditions

We can provide a complete glass microfluidic device & chip interface designed for droplets generation. We will study your request and give you further information and a quote. Please provide us with:

  • Your mask design
  • Specific requirements

Features and benefits

  • Hydrophobic or hydrophylic coatings
  • High chemical compatibility
  • High monodispersity droplets’ size
  • High droplet production rate
  • Operating pressure up to several decades of bar
  • Several chip layers thicknesses

More options available below

Applications of droplet generator

Single Cell manipulation

single cell plug and play microfluidic setup

Objects encapsulation

MICROFLUIDICS-DROPLET-DRIPPING-REGIME-T-JUNCTION-

Chemical microreactor

Introduction to lab-on-a-chip 2015  review history and future biomems

Chemotaxis

microfluidic-device-stamping-gradient-flow-control

Specific needs? Several options are available to upgrade your pack

This pack had been designed to fit the researchers’ most common needs in droplet generation. Feel free to contact us to discuss your specific needs ; if necessary we will adapt the pack and chips to your particular research applications. For your most common additional needs, we already offer the shelf option.

OPTION

microfluidic-sample-perfusion-injection-switch-valve for microfluidic droplet generation

OPTION

Microfluidic multiplexer MUX Flow switch

OPTION

OPTION

 Optical detection

10 sample switches

Adding Elveflow MUX distributors to this pack allows you to change the composition of your droplets between ten different samples during the same experiment.

Stop your droplets in 100 ms

Adding the Elveflow valve matrix allows you to start and stop your droplets in 100 ms. The use of the valve removes backflow and residual flow, and allows you to stop a fast flow.

Full custom OEM

Do you need a full custom OEM droplet generator for your commercial system ? We have a team with strong knowledge in droplet generation and industrialization. Feel free to contact us to discuss your specific needs.

Fluo droplet tracking

When adding our fluorescence optoreader to our pack, you can follow in real time the fluorescence signal of your droplets in your software. This system excites and collects the fluorescence signals of your droplets, then detects and quantifies any event of interest during your experiment.

WORLD LEADER IN HIGH PERFORMANCE MICROFLUIDIC FLOW CONTROL

We  provide the only microfluidic flow control system using Piezo technology that enables a blazing fast flow change in your microdevice.

Piezo electric microfluidics flow control

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